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Report of Eurocan Plus: feasibility study for the co-ordination of national cancer research
Peter Boyle on behalf of project participants Eurocan Plus
The process that led the presentation and the financing of the project: Eurocan + Plus from the sixth framework programme was launched by the European Parliament.
This report summarises the main findings and conclusions of the Eurocan + Plus project that ran between October 2005 and December 2007, and outlines the proposals for action in the short and long term.
Project participants represented themselves and not the institution where they work.The project was in no way a formal collaboration between any governmental body, funding agency, research or medical institution of the 27 Member States. in this regard, proposals in this brief and other deliverables in no way constitute a formal commitment all governmental or nongovernmental entity, for any idea proposed by the project.
For more information about the topics developed in this report, interested readers are invited to consult the reports of the different work packages. these reports can be consulted on the draft http://www.eurocanplus.eu website.
Volume: 2 article number: 84 DOI: 10.3332/eCMS. 2008.84 received: 09/05/2008 published: 20/05/2008
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Policy challenges for research on cancer: a call to arms
R. Sullivan
Research has delivered great benefits for cancer patients and their families, as James Watson and Francis Crick written now immortal line, “we want to propose a structure for deoxyribonucleic acid salt” setting so the molecular basis of the modern era of cancer control. The pace of technological innovation from fundamental scientific discoveries, the impact of the policy of massive population studies was breathtaking. One has only to do a book on the treatment of epithelial tumors solids, written by Henri Tagnon and colleagues in 1966 with the myriad of chemotherapy approaches available to oncologists today. Inevitably, as the tide of research has gone up so I bought the flotsam and jetsam of regulations and policies. Some were useful, many unnecessary and too many harmful effects. Of course some of these regulatory policies and General (why I mean those concerned with finance, structure and organization) has been specifically to cancer research, for example US National Cancer Act 1971, while others were a product of the overall regulatory environment with indirect consequences for research on cancer, 1995 EU directive e.g. data protection.So policy issues cover a vast area crossed by complex interdependencies between scientific areas, S & T policies of countries and socio-political constructs. Unfortunately there has been little attention to the consequences of these policy issues from which the research community in General, was a passenger, rather than the driver.
Volume: 1 article number: 53 DOI: 10.3332/53 ecancer. 2008. received: 12/08/2007 published: 18/09/2007
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A basic competence for research nurses education program: an Italian experience
S. Orlando Liptrott, l., m. Clerici, a. Cocquio, g. Martinelli
Background, the directive establishes the obligation of personnel working in the tests to be qualified by education, training, and experience [14]. This includes research nurse, however, in the transition from research department nurse nurse, new and highly developed skills and knowledge are needed to work effectively.
Methods was developed an education program, which included a review of current knowledge and practice basic skills development concerning the role of research nurse, haemato-Oncology and clinical trials education to support this advanced practice nursing in clinical studies.
Overall results, feedback on the course by nurses was very positive, and nurses were able to assume the role of nurse of research in clinical trials specified
Conclusions the role of research nurse is complex and varied. First nurse training does not cover all aspects to performance and skills essential for this role. to assess the requirements of nurses working in clinical studies and practice environment, it was possible to recognise prior training, skills and knowledge of nurses and to develop a program to complete this job-specific training and skills have been useful to clarify and define a key areas previously ill defined role and have helped these running as nurses nurse search within clinical trials.
Volume: 3 article number: 134 DOI: 10.3332/ecancer may.2009.134 received: 10/02/2009 published: 18/03/2009
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The development of an infrastructure of European network for research on cancer: vision, architecture and services
M. Rueping Tsiknakis, s., l. Martin, s. Sfakianakis, r. Sengstag Bucur, t., m. Pucaski Brochhausen, j., b. Graf
Life sciences are currently in the middle of a informational revolution. The nature and amount of information available now open directions of research that once were in the realm of science fiction.During this revolution statement, data collection capabilities have significantly exceeded the techniques of data analysis. integrating data between heterogeneous data sources and aggregation of data across different aspects of spectrum biomedical, therefore, is at the heart of current biomedical and pharmaceutical R&D.
This paper reports on the results of the integrated project ACGT original focusing on designing and developing a European biomedical grid infrastructure in support of multicentric, post genomic clinical cancer.Post-Genomic clinical trials (CTs) use clinical data and multilevel and advanced genomic analysis tools and computational view to verify the assumptions made in an attempt to identify the reasons for a disease molecular and stratification of patients in terms of treatment.
The document provides a presentation of the needs of users involved in CTs post-genomics and presents indicative scenarios that drive the requirements of the design phase of the project. Subsequently, presents the initial architecture specified by the project and its services are classified and discussed. a range of these key services, including the ontology master on cancer that is located in the heart of the architecture of integration of the project, are presented. Special efforts were taken to describe the technological and methodological framework of the project, allowing the creation of an infrastructure legally compliant and naive.
Finally, a brief discussion of the next job is included and describes the potential involvement of the cancer research community in the further development or the use of infrastructure.
Volume: 1 article number: 56 DOI: 10.3332/ecms. 2007.56 received: 15/07/2007 published: 21/09/2007
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